Characteristics of IV Antihypertensive agents
The following medicines are described for five effects
- Therapy class
- Onset of Action
- Duration of action
- Preload
- Afterload
Nicardipine is Dihydropyridine Calcium Channel Blocker with onset in 5-10 minute and duration of action 2-4 hours. It has No effect on Preload but decrease afterload.
Clevipidine Nicardipine is Dihydropyridine Calcium Channel Blocker with onset in 1 minute and duration of action 10 minutes. It has No effect on Preload but decrease afterload.
Esmolol is Dihydropyridine Beta Blocker with onset in 6-10 minutes and dutation of action 20 minutes. It has No effect on Preload or afterload.
Fenoldopam is Dihydropyridine Dopamine-D1 like receptor agonist with onset in 10-15 minutes and duration of action 10-15 minutes. It has No effect on Preload but decrease afterload.
Hydralazine is Arterial Vasodilator with onset in 10 minutes and duration of action 2-6 hours. It has No effect on Preload but decrease afterload.
Labetolol is Selective alpha and non-selective beta adrenergic receptor blocker with onset in 5-10 minutes and duration of action 2-6 hours. It has No effect on Preload but decrease afterload.
Nitroglycerine is Nitrovasodilator with onset in 2-5 minutes and duration of action 10-20 minutes. It has No effect on Preload and minimal effect on afterload.
Sodium nitroprusside is Nitrovasodilator with onset in few seconds and duration of action 1-2 minutes. It has decrease Preload and afterload.